Nutritional assessment as a complement to studies in populations exposed to oxidizing agents
DOI:
https://doi.org/10.14306/renhyd.17.4.21Keywords:
Nutrition Assessment, Nutrition Surveys, Diet Surveys, Occupational Exposure, Oxidative Stress.Abstract
Introduction: oxidative stress (OS) is associated with an imbalance between oxidation and antioxidant systems in favor to the former. The micronutrient dietary contribution could provide a protective effect against occupational exposure to oxidizing agents. The aim of this study was to determine the correlation between nutritional status, dietary and hygiene habits, macro and micronutrients intake and OS in a population exposed to oxidizing agents, compared with unexposed population.
Material and methods: two populations with similar characteristics were studied, except for the work activity of one of them, constituted for people of both sexes, of 18-30 years old. Exposed Group consisted of 26 individuals working in photocopying and Unexposed Group by 27 volunteers who do not perform such work activity. A nutritional survey, two reminders of 24 hours, anthropometric measurements and biochemical parameters, and a determination of OS markers (Catalase, GSH / GSSG and TBARS) was performed.
Results: to establish associations between variables, results were analyzed using multivariate statistics. Results show a positive correlation between work activity and oxidative imbalance and between high energy intake, low antioxidant micronutrients source intake, sedentary, altered lipid profile and OS. A positive relationship between low power intake, normal lipid profile and adequate fruits and vegetables intake with a normal oxidative state was show.
Conclusions: Results show that changes in hygiene and dietary habits may provide protection to individuals exposed to oxidizing agents.
References
Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, et al. Increase oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest. 2007; 114(12): 1752-61.
Mayne ST. Antioxidant nutrients y chronic disease: use of biomarkers of exposure and oxidative stress status in epidemiologic research. J Nutr. 2003; 133 (Suppl 3): 933S-40S.
Tepel M, Van der Giet M, Schwarzfeld C, Laufer U, Liermann D, Zidek W. Prevention of radiographic contrast agent induced reductions in renal function by acetylcysteine. N Engl J Med. 2000; 343(3): 180-4.
De las Heras G, García de la Paz A, Fernández MD, Fernández Foncelledo JL. Use of antioxidants to treat pain in chronic pancreatitis. Rev Esp Enferm Dig. 2000; 92(6): 375-85.
Messite J, Warshaw LJ. Enciclopedia de Salud y Seguridad en el Trabajo. Protección y promoción de la Salud, Programas de Nutrición en el Lugar de trabajo. Chantal Dufresne, BA. Madrid, 2001.
Lee R, Nieman DC.2007. Nutritional Assessment: Meas uring Diet. Ed. L Meyers. 4 ed. New York. McGraw-Hill. p. 33-89.
Argenfood. Tabla de Composición de Alimentos. Acceso: mayo de 2013. Disponible en: http://www.unlu.edu.ar/~argenfood/ Tablas/Tabla.htm.
Suárez MM, López LB. Alimentación saludable: guía práctica para su realización. Hipocrático S.A. Buenos Aires, 2009.
Resolución 145/03 del Ministerio de Salud de la Nación, Reglamento General para el transporte de mercancías peligrosas por carretera y la Norma IRAM 80058-1.
Aebi HE. Catalase in vitro. Meth Enzymol. 1984; 105: 121-6.
Buege JA, Aust SD. Microsomal lipid peroxidation. Meth Enzymol. 1978; 52: 302-10.
Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959; 82(1): 70-7.
Venturino A, Anguiano OL, Gauna L, Cocca C, Bergoc RM, Pechen de D’Angelo AM. Thiols and polyamines in the potentiation of malathion toxicity in larval stages of the toad Bufo arenarum. Comp Biochem Physiol C Toxicol Pharmaco. 2001; 130(2): 191-8.
OMS 2003: OMS, Informe Técnico 916, Dieta, Nutrición y Prevención de Enfermedades Crónicas 2003. Disponible en: ftp. fao.org/docrep/fao/006/ac911s/ac911s00.pdf. [Consultado 14 de agosto de 2009].
Torresani ME, Somoza MI. Lineamientos para el cuidado nutricional. 2° ed. Eudeba. Buenos Aires, 2003.
Barbosa KBF, Bressan J, Zulet MA, Martinez JA. Influencia de la dieta sobre marcadores plasmáticos de estrés oxidativo en humanos. An Sist Sanit Navar. 2008; 31: 259-280.
Hyun DH, Emerson SS, Jo DG, Mattson MP, de Cabo R. Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc Natl Acad Sci USA. 2006; 103 (52): 19908-12.
Crujeiras AB, Parra D, Abete I, Martinez JA. A hypocaloric diet enriched in legumes specifically mitigates lipid peroxidation in obese subjects. Free Radic Res 2007; 41(4): 498-506.
Rodríguez Perón JM, Menéndez López JR, Trujillo López Y. Radicales libres en la biomedicina y estrés oxidativo. Rev Cubana Med Milit. 2001; 30 (1): 36-44.
Hu Y, Block G, Norkus EP, Morrow JD, Dietrich M, Jhudes M. Relations of glycemic index and glycemic load with plasma oxidative stress markers. Am J Clin Nutr 2006; 84(1): 70-6.
Roberts CK, Barnard RJ, Sindhu RK, Jurczak M, Ehdaie A, Vaziri ND. A high-fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression. J Appl Physiol (1985). 2005; 98(1): 203-10.
Espinosa Hernández JA, Cué Brugueras M. Vitaminas y minerales contra el estrés. Rev Cub Farm. 2001; 35 (1): 74- 78.
Opara EC. Oxidative stress, micronutrients, diabetes mellitus and its complications. J R Soc Promot Health. 2002; 122(1): 28-34.
Rodrigo R, Guichard C, Charles R. Clinical pharmacology and therapeutic use of antioxidant vitamins. Fundam Clin Pharmacol. 2007; 21(2): 111-27.
Bunout D, Garrido A, Suazo M, Kauffman R, Venegas P, De La Maza P et al. Effects of supplementation with folic acid and antioxidant vitamins on homocysteine levels and LDL oxidation in coronary patients. Nutrition. 2000; 16(2): 107-10.
Actis Goretta L, Carrasquedo F, Fraga CG. The regular supplementation with an antioxidant mixture decreases oxidative stress in healthy humans. Gender effect. Clin Chim Acta. 2004; 349(1-2): 97-103.
Huang HY, Appel LJ, Croft KD, Miller ER, Mori TA, Puddey IB. Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial. Am J Clin Nutr. 2002; 76(3): 549-55.
Dunstan JA, Breckler L, Hale J, Lehmann H, Franklin P, Lyons G et al. Supplementation Mwith vitamins C, E, beta-carotene and selenium has no effect on antioxidant status and immune responses in allergic adults: a randomized controlled trial. Clin Exp Allergy. 2007; 37(2): 180-7.
Cuevas Gonzales S. Análisis de los factores de riesgo cardiovascular en el proceso de envejecimiento y su relación con el estrés oxidativo. Estudio piloto observacional. (Trabajo para optar por el título de Doctor en Cs. Médicas). 2008. Facultad de medicina, departamento de fisiologia, universidad de Murcia, España.
Fernández Gonzáles JL, Delgado Rodríguez AE, García Portela R, Brown Sotolongo C, Pimentel OL, Flores Podadera H. Estrés oxidativo, enfermedad pulmonar obstructiva crónica y tabaquismo. Rev Cub Med. 2002; 41: 3-7.
Lebredo Alvarez I, Herrera BA, Céspedes M, Puldon S. Variables de estrés oxidativo en conejos tratados con etanol y dieta hipercolesterolémica. Rev Cub Invest Biomed. 2003: 22(4): 253-258.
Wu D, Cederbaum AI. Alcohol, oxidative stress, and free radical damage. Alcohol Res Health. 2003; 27 (4): 277-84.
Aldred S. Oxidative and nitrative changes seen in lipoproteins following exercise. Atherosclerosis. 2007; 192(1): 1-8.
Martínez Abundis E, Sánchez Rodríguez MA, Hafidi Bentlakder ME. Participación de la mitocondria en el desarrollo de estrés oxidativo en la obesidad. Bioquimia. 2005; 30(3): 82- 89.
Zhou JF, Cai D, Tong GZ. Oxidative stress and potential free radical damage associated with photocopying. A rol for ozone?. Free Radic Res. 2003; 37(2): 137-43.
Zhou JF, Chen WW, Tong GZ. Ozone emitted during copying process - a potential cause of pathological oxidative stress and potential oxidative damage in the bodies of operators. Biomed Environ Sci. 2003; 16(2): 95-104.
Cavia M, López Muñoz AM, Hernando B, López AS, García Girón C, Coma MJ . Estado redox celular y cáncer. Influencia sobre el tratamiento con citostáticos. Rev Electron Biomed. 2007; 2: 51-55.
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