Number of years with type 2 diabetes is associated with cognitive impairment in Chilean older adults: A cross-sectional study
DOI:
https://doi.org/10.14306/renhyd.25.3.1256Keywords:
Aging, Cognitive Dysfunction, Diabetes Mellitus, Type 2Abstract
Introduction: The average life expectancy, as well as the prevalence of Type 2 diabetes (T2D), is increasing worldwide. Population-based studies have demonstrated that the duration of T2D has been associated with cognitive impairment. However, despite the high prevalence of T2D and cognitive impairment in Chile, the association between years with T2D and suspicion of cognitive impairment has not yet been investigated. The objective of this study was to investigate the association between duration of T2D and suspicion of cognitive impairment in Chilean older adults.
Material and Methods: 1,040 older adults aged ≥60 years from the Chilean National Health Survey (2009–2010) were included. Suspicion of cognitive impairment was assessed by the abbreviated Mini-Mental State Examination (MMSE). The number of years with T2D was self-reported and categorised into four groups. Poisson Regression analysis was used to assess the association between altered MMSE and the number of years with DM2, adjusted by potential confounders including socio-demographic, lifestyle, adiposity and health-related factors.
Results: When the analyses were adjusted for socio-demographic factors, people who had T2D for 15 to 24 and ≥25 years had 2.2-times (95% CI: 1.07; 3.33) and 5.8-times (95% CI: 3.81; 11.0) higher relative risk (RR) of cognitive impairment, compared to those without T2D. When the analyses were additionally adjusted for lifestyle and health-related covariates, the RR for cognitive impairment was 1.76-times (95% CI: 1.02; 2.50) and 4.54-times (95% CI: 2.70; 6.38) higher for those who had T2D for 14-24 years and ≥25 years, respectively.
Conclusions: Number of years with T2D was associated with suspicion of cognitive impairment. A longer duration of T2D was associated with a higher likelihood of cognitive impairment in the Chilean older population, independently of confounder factors included in the study.
Author Biography
Fanny Petermann Rocha, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UKBritish Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK; Facultad de Medicina, Universidad Diego Portales, Santiago, Chile.
Nombre: Fanny Petermann-Rocha
Afiliación:College of Medical, Veterinary and Life Sciences, University of Glasgow
Correo electrónico:f.petermann-rocha.1@research.gla.ac.uk
Líneas o intereses de investigación: Envejecimiento, estilos de vida, enfermedades crónicas no transmisibles, epidemiología nutricional.
Enlace a perfil de Twitter: @Fanny_Petermann
ORCID: https://orcid.org/0000-0002-4384-4962
Research ID:-
Enlace a pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=%28Fanny+Petermann%29+OR+%28Fanny+Petermann-Rocha%29
Link a cuadro de conflictos de interés: http://www.renhyd.org/index.php/renhyd/pages/view/editorCOIs#fpetermann
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Copyright (c) 2021 Agnieszka Bozanic, Fanny Petermann Rocha, Heather Waddell, Solange Parra-Soto, Carla Cuevas, Claire Richardson, María Adela Martínez-Sanguinetti, Ana María Leiva-Ordoñez, Gabriela Nazar, Claudia Troncoso, Lorena Mardones, Marcelo Villagrán, Miquel Martorell, Eva Ariño Mateo, Carolina Ochoa-Rosales, Ximena Díaz-Martinez, Natalia Ulloa, Carlos Celis-Morales
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