Influence of psychotropic drugs prescription on body weight increase
DOI:
https://doi.org/10.14306/renhyd.17.1.4Keywords:
Anticonvulsants, antidepressants, antipsychotics, anxiolytics, mood stabilizers, morbidity, obesity, psychotropic drugsAbstract
Obesity has become a major public health burden, not only by the rising prevalence but also because of the associated complications. Furthermore there is a number of diseases whose risk and onset is increased in subjects with overweight such as type 2 diabetes, dislipemias, tumors (endometrial, colon, breast, cancer, etc), skeletal disorders, digestive disturbances, cardiovascular diseases, respiratory disorders, psychological problems, obstetric and gynecological disorders.
The prescription of psychotropic drugs is important and, in most countries, consumption has been increased in recent years. Indeed, several drugs used in the treatment of anxiety, depression, bipolar disorder, schizophrenia or epilepsy, can increase body weight and fat deposition or eventually decrease it. These side effects could make a previous situation of obesity to worsen, and it can even cause excessive weight gain in patients with a normal weight at the beginning of the treatment. This increase in adiposity may also contribute to the lack of adherence to the medication and thus a possible relapse of the patients.
In this review we report the links between psychotropic drugs administration and weight gain as well as the potential mechanisms that are involved.
DOI: http://dx.doi.org/10.14306/renhyd.17.1.4
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