Comparison of metabolic effects of bariatric surgery in a group of elderly and young adults: A prospective cohort
DOI:
https://doi.org/10.14306/renhyd.25.1.1036Keywords:
Bariatric Surgery, Body Mass Index, Diabetes Mellitus, Type 2, Aged, Weight LossAbstract
Introduction: The aim was to evaluate metabolic parameters in a group of patients older than 65 years old compared to younger adults at three and six months after bariatric surgery (BS).
Materials and methods: Prospective analytic study of a cohort of 40 patients under BS since 2015 to 2018. Participants were divided into two groups (Group A: ≥65; B: <65 years old). Anthropometrics and metabolic parameters were assessed before and 3 and 6 months after BS. The excess weight loss percentage (EWLP) and the Triglycerides/HDLc ratio, as a marker of insulin resistance, were also evaluated. A p <0.05 was statistically significant.
Results: Forty patients were under BS, we included thirty six: 21 patients were at group A (Median age: 59, RIQ: 48-61 years old) and 15 at group B (median age 67, RIQ: 66-69 years old), the prevalence of patients with type 2 diabetes was 53% (n=8) in group B vs 43% (n=9) at group A. After 3 and 6 months of BS, we found no statistical difference between groups in WL and the EWLP and the decrease in fasting blood glucose (FBG), HbAc1 % levels but a significant rise in the levels of HDLc in group B. We observed a statistically decrease in the TAG/HDLc ratio and a positive correlation between HbA1c% and levels of FBG, HDLc and the TAG/HDLc ratio in group B. Moreover, we found a reduction in the use of antidiabetics and lipid lowering drugs in this age group.
Conclusion: We found a significant benefit in metabolic effects of BS in the≥65 y/o cohort, especially by decreasing insulin resistance, even in those patients without diagnosis of DM2. We need more studies and a greater sample size to generalize these results.
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