Influence of malnutrition on the quality of life for the cancer patient before the beginning of the chemotherapy/radiotherapy treatment

Authors

  • Cristina Ortega Ibañez Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Lira Pelari Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Giovanna Cadeddu Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Patricia Barrionuevo Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Ainhoa González Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Ángela Aguado Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Margarita Martín Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.
  • Sonsoles Sancho Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

DOI:

https://doi.org/10.14306/renhyd.25.1.1061

Keywords:

Malnutrition, Quality of Life, Neoplasms, Patients, Radiotherapy, Antineoplastic Agents, Oncological patient, EORTC QLQ c-30

Abstract

Introduction: The measurement of the quality of life (QL) in the oncological patient makes it possible to establish an individual’s perception of his state of health - illness and the treatment instituted. The aim of this study is to analyze the influence of nutritional status on the QL of patients.

Material and methods: A transversal study was carried out at the Ramón y Cajal Hospital in 53 oncological patients over a period of 6 months. These patients were given the global subjective assessment (VGS), a 24-hour memory of the previous day’s intake, and were given the European Organisation for Research and Treatment of Cancer quality of Life Questionnaire Core 30 (EORTC QLQ-C30). Of these 53 patients, 9 were excluded due to incomplete completion of the EORTC QLQ C-30 questionnaire. Of the remaining 44 patients, 52.3% belonged to the group of safe normonutrids (SGA A); 27.3% to the group of patients at risk of malnutrition(SGA B) and the remaining 20,5% to the group of patients with severe malnutrition (SGA C).

Results: The functional scales (physical, social, emotional and cognitive functioning) were least affected by the nutritional status of the patients, with a value of p>0.05, while the functional or role scale (p 0.002), together with the overall health scale (p 0.049), as well as the symptoms of fatigue (p 0.011), nausea and vomiting (p 0.004) and the simple item of loss of appetite (p 0.001) are those that showed a statistically significant association with nutritional status.

Conclusions: Malnutrition negatively affects the QL of oncology patients especially on the functional, overall health and symptom scales. More studies are needed to assess whether early nutritional intervention can reverse this negative influence of malnutrition.

Author Biographies

Cristina Ortega Ibañez, Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Nutricionista

Lira Pelari, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Médico Interno Residente

Giovanna Cadeddu, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Médico Interno Residente

Patricia Barrionuevo, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Médico Interno Residente.

Ainhoa González, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Enfermera

Ángela Aguado, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Enfermera

Margarita Martín, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Médico adjunto

Sonsoles Sancho, Servicio de Oncología Radioterápica, Hospital Universitario Ramón y Cajal. Madrid, Spain.

Servicio de Oncología Radioterápica. Jefe de Servicio

References

(1) Gómez Candela C, Olivar Roldán J, García M, Marín M, Madero R, Pérez-Portabella C, et al. Utilidad de un método de cribado de malnutrición en pacientes con cáncer. Nutr Hosp. 2010; 25 (3): 400-5.

(2) Arends J, Bachmann P, Baracos V, Barthelemy N, Bertz H, Bozzetti F et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017;36(1):11-48.

(3) Cáceres Lavernia H, Neninger Vinageras E, Menéndez Alfonso Y, Barreto Penié J. Nutritional intervention in cancer patient. Rev cubana med. 2016;55(1): 59-73.

(4) Osoba, D. Measuring the effect of cancer on quality of life. En D. Osoba (Ed.), Effect of cancer on quality of life. 1991: 25-40.

(5) World Health Organization. World Health Organization Quality of life Assessment (WHOQOL): Position paper from the World Health Organization. Soc Sci Med. 1995;41:1403-9.

(6) Sprangers MA, Cull A, Bjordal K, Groenvold M, Aaronson NK. The European Organization for Research and Treatment of Cancer. Approach to quality of life assessment: guidelines for developing questionnaire modules. EORTC Study Group on Quality of Life. Qual Life Res. 1993;2(4):287-295.

(7) Aaronson N, Cull A, Kaasa S, Sprangers M. The EORTC modular approach to quality of life assessment in Oncology. Int J Ment Health. 1994; 23 (2): 75-96.

(8) Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst. 1993;85(5):365-76.

(9) Arraras JI, Arias F, Tejedor M, Pruja E, Marcos M, Martínez E, et al. The EORTC QLQ-C30 (version 3.0) Quality of Life questionnaire: validation study for Spain with head and neck cancer patients. Psychooncology. 2002;11(3):249-56.

(10) Cruz Bermudez HF, Moreno Collazos JE, Angarita Fonseca A. Medición de la calidad de vida por el cuestionario QLQ-C30 en sujetos con diversos tipos de cáncer de la ciudad de Bucaramanga-Colombia. Enferm Glob. 2013; 12 (30): 294-303.

(11) Fayers PM, Aaronson NK, Bjordal K, Groenvold M, Curran D, Bottomley A, on behalf of the EORTC Quality of Life Group. The EORTC QLQ-C30 Scoring Manual (3rdEdition). European Organisation for Research and Treatment of Cancer, Brussels 2001. Disponible en: https://www.eortc.org/app/uploads/sites/2/2018/02/SCmanual.pdf

(12) Davudov MM, Harirchi I, Amiraliyev N, Mehtiyeva E, Mirzajani Z, Amiraliyev K, et al. The Azeri Version of European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30): Translation and Validation. Asian Pac J Cancer Prev. 2020;21(1):267-71.

(13) Bedard G, Zeng L, Zhang L, Lauzon N, Holden L, Tsao M, et al. Minimal important differences in the EORTC QLQ-C30 in patients with advanced cancer. Asia Pac J Clin Oncol. 2014;10(2):109-17.

(14) Sat-Muñoz D, Morán Mendoza Ade, Solano-Murillo P, Balderas-Peña LM, Rivera-Morales D, Iñíguez-Virgen A, et al. Papel del cuestionario EORTC QLQ-C30 en la predicción de riesgo de desnutrición en pacientes mexicanos con cáncer de cabeza y cuello. Nutr Hosp. 2012;27(2):477-82.

(15) Polański J, Jankowska-Polańska B, Uchmanowicz I, Chabowski M, Janczak D, Mazur G, et al. Malnutrition and Quality of Life in Patients with Non-Small-Cell Lung Cancer. Adv Exp Med Biol. 2017;1021:15-26.

(16) Guo ZQ, Yu JM, Li W, Fu ZM, Lin Y, Shi YY, et al. Survey and analysis of the nutritional status in hospitalized patients with malignant gastric tumors and its influence on the quality of life. Support Care Cancer. 2020;28(1):373-80.

(17) Schulz KH, Patra S, Spielmann H, Klapdor S, Schlüter K, van Eckert S. Physical condition, nutritional status, fatigue, and quality of life in oncological out-patients. SAGE Open Med. 2017;5:2050312117743674.

(18) Jin S, Lu Q, Pang D, Sun Y, Xiao S, Zheng B, et al. Validation of the Chinese version of the Head and Neck Patient Symptom Checklist for measuring nutrition impact symptoms during radiotherapy in patients with head and neck cancer. Support Care Cancer. 2019;27(12):4705-11.

(19) Derogar M, van der Schaaf M, Lagergren P. Reference values for the EORTC QLQ-C30 quality of life questionnaire in a random sample of the Swedish population. Acta Oncol. 2012;51(1):10-16.

(20) Campos JADB, Silva WRD, Spexoto MCB, Serrano SV, Marôco J. Clinical, dietary and demographic characteristics interfering on quality of life of cancer patients. Einstein. 2018;16(4):eAO4368.

(21) Calderon C, Carmona-Bayonas A, Beato C, Ghanem I, Hernandez R, Majem M, et al. Risk of malnutrition and emotional distress as factors affecting health-related quality of life in patients with resected cancer. Clin Transl Oncol. 2019;21(5):687-691.

Published

2021-03-31

How to Cite

Ortega Ibañez, C., Pelari, L., Cadeddu, G., Barrionuevo, P., González, A., Aguado, Ángela, Martín, M., & Sancho, S. (2021). Influence of malnutrition on the quality of life for the cancer patient before the beginning of the chemotherapy/radiotherapy treatment. Spanish Journal of Human Nutrition and Dietetics, 25(1), 39–47. https://doi.org/10.14306/renhyd.25.1.1061