Asociación de diversidad y calidad dietética con rendimiento cognitivo y probabilidades de enfermedad de Alzheimer: Estudio transversal.
DOI:
https://doi.org/10.14306/renhyd.28.3.2144Palabras clave:
Índice de calidad dietética, Diversidad dietética, Índice de alimentación saludable, Enfermedad de AlzheimerResumen
Introducción. La evidencia científica propone que una dieta sana y diversa puede tener un papel fundamental en la preservación del rendimiento cerebral y cognitivo. Intentamos investigar la asociación entre la diversidad y la calidad de la dieta con el rendimiento cognitivo y las probabilidades de padecer la enfermedad de Alzheimer (EA).
Metodología. Estudio transversal con 89 participantes (60 pacientes con Alzheimer y 29 individuos sanos) mayores de 60 años (38 hombres y 51 mujeres). Se utilizó un registro alimentario de tres días para evaluar la ingesta dietética de los participantes. La puntuación de diversidad dietética (DD) se examinó utilizando las directrices de la FAO (Organización para la Alimentación y la Agricultura) y la calidad de la dieta se evaluó mediante el índice de alimentación saludable (HEI) y el índice de calidad dietética (DQI). El rendimiento cognitivo se evaluó mediante el Mini-Mental State Test (MMSE).
Resultados. La puntuación DD fue significativamente menor en el grupo AD que en el grupo sano (p<0,001). Sin embargo, no hubo diferencias significativas en las puntuaciones de HEI y DQI entre los grupos con EA y sanos (p>0,05). Hubo una asociación significativa entre la puntuación DD con la puntuación total del MMSE (β= 0,33, p=0,02), la memoria (β=0,35, p=0,02) y el lenguaje (β= 0,32, p=0,03). El IES se correlacionó positivamente con el cálculo (β= 0,32, p=0,02). Un DD alto redujo las probabilidades de EA en un 79% (OR: 0,21; IC del 95%: 0,10, 0,42; p<0,001) en un modelo multivariado.
Conclusión. Un DD alto puede estar asociado con un mejor estado cognitivo y una reducción de las probabilidades de padecer EA.
Financiamiento: Universidad de Ciencias Médicas de Tabriz.
Citas
Li X, Feng X, Sun X, Hou N, Han F, Yongping Liu Y. Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2019. Front Aging Neurosci. 2022:14:937486. doi: 10.3389/fnagi.2022.937486.
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, et al. New insights into the genetic etiology of Alzheimer’s disease and related dementias. Nat Genet. 2022;54,412–436. https://doi.org/10.1038/s41588-022-01024-z
Abate G, Marziano M, Rungratanawanich W, Memo M, Uberti D. Nutrition and AGE-ing: focusing on Alzheimer’s disease. Oxid Med Cell Longev. 2017:7039816. https ://doi.org/10.1155/2017/7039816
Smith PJ, Blumenthal JA. Dietary factors and cognitive decline. J Prev Alzheimers Dis. 2016; 3(1): 53–64. doi: 10.14283/jpad.2015.71
Duplantier SC, Gardner CD. A critical review of the study of neuroprotective diets to reduce cognitive decline. Nutrients. 2021; 13(7): 2264. doi: 10.3390/nu13072264
Kheirouri S, Alizadeh M. MIND diet and cognitive performance in older adults: a systematic review. Crit Rev Food Sci Nutr. 2022;62(29):8059-8077. doi: 10.1080/10408398.2021.1925220.
Kennedy G, Ballard T, Dop M. Nutrition and Consumer Protection Division, Food and Agriculture Organization of the United Nations. Guidelines for Measuring Household and Individual Dietary Diversity. Rome 2011 [cited 1/23/2024]; Available in: https://www.fao.org/3/i1983e/i1983e00.pdf
Wirt A, Collins CE. Diet quality – what is it and does it matter? Public Health Nutr. 2009;12(12):2473-92. doi: 10.1017/S136898000900531X.
Azadbakht L, Mirmiran P, Azizi F. Dietary diversity score is favorably associated with the metabolic syndrome in Tehranian adults. Int J Obes (Lond). 2005;29(11):1361-7. doi: 10.1038/sj.ijo.0803029.
Qorbani M, Mahdavi-Gorabi A, Khatibi N, Ejtahed H-S, Khazdouz M, Djalalinia S, et al. Dietary diversity score and cardio-metabolic risk factors: an updated systematic review and meta-analysis. Eat Weight Disord. 2022;27(1):85-100. doi: 10.1007/s40519-020-01090-4.
Drewnowski A, Fiddler EC, Dauchet L, Galan P, Hercberg S. Diet quality measures and cardiovascular risk factors in France: Applying the healthy eating index to the SU.VI.MAX study. J Am Coll Nutr. 2009;28(1):22-9. doi: 10.1080/07315724.2009.10719757.
Dalwood P, Marshall S, Burrows TL, McIntosh A, Collins CE. Diet quality indices and their associations with health-related outcomes in children and adolescents: an updated systematic review. Nutr J. 2020;19(1):118. doi: 10.1186/s12937-020-00632-x.
Harrison S, Couture P, Lamarche B. Diet quality, saturated fat and metabolic syndrome. Nutrients. 2020 Oct 22;12(11):3232. doi: 10.3390/nu12113232.
Qu X, Na X, Yang J, Yu H, Chen A, Zhao A. Reaching and maintaining higher dietary diversity is associated with decreased risk of all-cause mortality: A longitudinal study from the China Health and Nutrition Survey. Front Nutr. 2022:9:947290. doi: 10.3389/fnut.2022.947290.
Liu YH, Gao X, Na M, Kris-Etherton PM, Mitchell DC, Jensen GL. Dietary pattern, diet quality, and dementia: A systematic review and meta-analysis of prospective cohort studies. J Alzheimers Dis. 2020;78(1):151-168. doi: 10.3233/JAD-200499.
Petersen KS, Kris-Etherton PM. Diet quality assessment and the relationship between diet quality and cardiovascular disease risk. Nutrients. 2021;13(12):4305. doi: 10.3390/nu13124305.
Azadbakht L, Mirmiran P, Esmaillzadeh A, Azizi F. Dietary diversity score and cardiovascular risk factors in Tehranian adults. Public Health Nutr. 2006;9(6):728-36. doi: 10.1079/phn2005887.
Otsuka R, Nishita Y, Tange C, Tomida M, Kato Y, Nakamoto M, et al. Dietary diversity decreases the risk of cognitive decline among Japanese older adults. Geriatr Gerontol Int. 2017;17(6):937-944. doi: 10.1111/ggi.12817.
Krebs-Smith SM, Pannucci TE, Subar AF, Kirkpatrick SI, Lerman JL, Tooze JA, et al. Update of the Healthy Eating Index: HEI-2015. J Acad Nutr Diet. 2018;118(9):1591-1602. doi: 10.1016/j.jand.2018.05.021.
Foroumandi E, Alizadeh M, Kheirouri S. Dietary quality index is negatively associated with serum advanced glycation end products in healthy adults. Clin Nutr ESPEN. 2020:36:111-115. doi: 10.1016/j.clnesp.2020.01.007.
Feldman HH, Baelen BV, Kavanagh SM, Torfs KEL. Cognition, function, and caregiving time patterns in patients with mild-to-moderate Alzheimer disease: a 12-month analysis. Alzheimer Dis Assoc Disord. 2005;19(1):29-36. doi: 10.1097/01.wad.0000157065.43282.bc.
Zhang J, Zhao A, Wu W, Yang C, Ren Z, Wang M, et al. Dietary diversity is associated with memory status in Chinese adults: A prospective study. Front Aging Neurosci. 2020:12:580760. doi: 10.3389/fnagi.2020.580760.
Zheng J, Zhou R, Li F, Chen L, Wu K, Huang J, et al. Association between dietary diversity and cognitive impairment among the oldest-old: Findings from a nationwide cohort study. Clin Nutr. 2021;40(4):1452-1462. doi: 10.1016/j.clnu.2021.02.041.
Liu D, Zhang W-T, Wang J-H, Shen D, Zhang P-D, Li Z-H, et al. Association between dietary diversity changes and cognitive impairment among older people: Findings from a nationwide cohort study. Nutrients. 2022;14(6):1251. doi: 10.3390/nu14061251.
Omar SH. Mediterranean and MIND diets containing olive biophenols reduces the prevalence of Alzheimer’s disease. Int J Mol Sci. 2019;20(11):2797. doi: 10.3390/ijms20112797.
Haring B, Wu C, Mossavar-Rahmani Y, Snetselaar L, Brunner R, Wallace RB, et al. No association between dietary patterns and risk for cognitive decline in older women with 9-year follow-uUp: Data from the women’s health initiative memory study. J Acad Nutr Diet. 2016;116(6):921-930.e1. doi: 10.1016/j.jand.2015.12.017.
Richard EL, Laughlin GA, Kritz-Silverstein D, Reas ET, Barrett-Connor E, McEvoy LK. Dietary patterns and cognitive function among older community-dwelling adults. Nutrients. 2018;10(8):1088. doi: 10.3390/nu10081088.
Estrella ML, Durazo-Arvizu RA, Mattei J, Mossavar-Rahmani Y, Perreira KM, Siega-Riz AM, et al. Alternate healthy eating index is positively associated with cognitive function among middle-aged and older hispanics/latinos in the HCHS/SOL. J Nutr. 2020;150(6):1478-1487. doi: 10.1093/jn/nxaa023.
van de Rest O, Berendsen AA, Haveman-Nies A, de Groot LC. Dietary patterns, cognitive decline, and dementia: A systematic review. Adv Nutr. 2015;6(2):154-68. doi: 10.3945/an.114.007617.
Liu YH, Gao X, Na M, Kris-Etherton P, Mitchell D. Dietary pattern score, diet quality, and major neurodegenerative diseases: A meta-analysis of observational cohort studies (OR33-07-19). Curr Dev Nutr. 2019; 3(Suppl 1): nzz039.OR33-07-19. doi: 10.1093/cdn/nzz039.OR33-07-19
Vega-Cabello V, Struijk EA, Caballero FF, Yévenes-Briones H, Ortolá R, Calderón-Larrañaga A, et al. Diet quality and multimorbidity in older adults: A prospective cohort study. J Gerontol A Biol Sci Med Sci. 2024;79(5):glad285. doi: 10.1093/gerona/glad285.
Hossain S, Beydoun MA, Weiss J, Kuczmarski MF, Evans MK, Zonderman AB. Longitudinal associations between dietary quality and Alzheimer’s Disease genetic risk on cognitive performance among African American adults. Br J Nutr. 2020; 124(12): 1264–1276. doi: 10.1017/S0007114520001269
Huang WJ, Zhang X, Chen WW. Role of oxidative stress in Alzheimer’s disease. Biomed. Rep. 2016;4:519–522. doi: 10.3892/br.2016.630.
Zhang W, Xiao D, Mao Q, Xia H. Role of neuroinflammation in neurodegeneration development. Signal Transduct Target Ther. 2023;8(1):267. doi: 10.1038/s41392-023-01486-5.
Koul B, Farooq U, Yadav D, Song M. Phytochemicals: A promising alternative for the prevention of Alzheimer’s disease. Life (Basel). 2023; 13(4): 999. doi: 10.3390/life13040999
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